Top AI Repos — open-source AI, indexed and scored
Top AI Repos tracks AI repositories on GitHub and answers two different questions about each one: is it moving right now, and would you bet a product on it.
Top AI Repos tracks AI repositories on GitHub and answers two different questions about each one: is it moving right now, and would you bet a product on it.
The world's most powerful open-source bio AI assistant - Access academic literature, clinical trials, drug labels, and more, all through natural conversation.
| Date | Stars |
|---|---|
| 2026-07-31 | 334 |
| 2026-08-05 | 337 |
| 2026-08-06 | 337 |
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<p align="center"> <a href="https://github.com/yorkeccak/bio/stargazers"><img src="https://img.shields.io/github/stars/yorkeccak/bio?style=flat&color=yellow" alt="GitHub Stars"></a> <a href="https://github.com/yorkeccak/bio/blob/main/LICENSE"><img src="https://img.shields.io/github/license/yorkeccak/bio" alt="License"></a> <a href="https://github.com/yorkeccak/bio/network/members"><img src="https://img.shields.io/github/forks/yorkeccak/bio?style=flat" alt="Forks"></a> <a href="https://github.com/yorkeccak/bio/graphs/contributors"><img src="https://img.shields.io/github/contributors/yorkeccak/bio" alt="Contributors"></a> </p> # Bio Try the hosted version [here](https://bio.valyu.ai) 🙌 Then fork and get building... > **Enterprise-grade biomedical research behind a chat interface** - Access PubMed, clinical trials, FDA drug labels, and run complex Python analyses through natural language. Powered by specialized biomedical data APIs.  ## Why Bio? Traditional biomedical research and data is fragmented across dozens of databases and platforms. Bio changes everything by providing: - **Comprehensive Medical Data** - PubMed articles, ClinicalTrials.gov data, FDA drug labels, and more - **One Unified Search** - Powered by Valyu's specialized biomedical data API - **Advanced Analytics** - Execute Python code in secure Daytona sandboxes for statistical analysis, pharmacokinetic modeling, and custom calculations - **Interactive Visualizations** - Beautiful charts and dashboards for clinical data - **Real-Time Intelligence** - Web search integration for breaking medical news - **Local AI Models** - Run with Ollama or LM Studio for unlimited, private queries using your own hardware - **Natural Language** - Just ask questions like you would to a colleague ## Key Features ### Powerful Biomedical Tools - **PubMed & ArXiv Search** - Access to millions of scientific papers and biomedical research - **Clinical Trials Database** - Search ClinicalTrials.gov for active and completed trials - **FDA Drug Labels** - Access comprehensive drug information from DailyMed - **Drug Information** - Detailed medication data, warnings, and contraindications - **Interactive Charts** - Visualize clinical data, drug efficacy, patient outcomes - **Python Code Execution** - Run pharmacokinetic calculations, statistical analyses, and ML models ### Advanced Tool Calling - **Python Code Execution** - Run complex biomedical calculations, statistical tests, and data analysis - **Interactive Charts** - Create publication-ready visualizations of clinical data - **Multi-Source Research** - Automatically aggregates data from multiple biomedical sources - **Export & Share** - Download results, share analyses, and collaborate ## Quick Start (Self-Hosted) Self-hosted mode is the recommended way to run Bio. It provides a complete local environment with: - **No authentication required** - Auto-login as dev user - **Local SQLite database** - No external database setup needed - **Unlimited queries** - No rate limits - **Ollama/LM Studio support** - Use local LLMs for privacy and unlimited usage ### Prerequisites - Node.js 18+ - pnpm (`npm install -g pnpm`) - Valyu API key (get one at [platform.valyu.ai](https://platform.valyu.ai)) - [Daytona](https://www.daytona.io) API key - used for secure sandboxed Python code execution (get one at [app.daytona.io](https://app.daytona.io)) - [Ollama](https://ollama.com) or [LM Studio](https://lmstudio.ai) installed (optional but recommended) ### Installation 1. **Clone the repository** ```bash git clone https://github.com/yorkeccak/bio.git cd bio ``` 2. **Install dependencies** ```bash pnpm install ``` 3. **Set up environment variables** Create a `.env.local` file in the root directory: ```env # Enable Self-Hosted Mode NEXT_PUBLIC_APP_MODE=self-hosted # Valyu API Configuration (Required) VALYU_API_KEY=your-valyu-api-key # Daytona Configu
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Read on GitHubWould you bet a product on this? Bounded 0–100 and slow moving.
matched fp:2c43544ac6ee8d16, llm:Repository topics: academic-paper, ai, ai-agents, bio-ai, drug-design, drug-discovery, healthcare-ai; description: 'The world's most powerful open-source bio AI assistant - Access academic literature, clinical trials, drug labels, and more, all through natural conversation.'
matched fp:2c43544ac6ee8d16, llm:Repository topics: academic-paper, ai, ai-agents, bio-ai, drug-design, drug-discovery, healthcare-ai; description: 'The world's most powerful open-source bio AI assistant - Access academic literature, clinical trials, drug labels, and more, all through natural conversation.'
matched fp:2c43544ac6ee8d16, llm:Repository topics: academic-paper, ai, ai-agents, bio-ai, drug-design, drug-discovery, healthcare-ai; description: 'The world's most powerful open-source bio AI assistant - Access academic literature, clinical trials, drug labels, and more, all through natural conversation.'